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Comparing Ventricular Function in Fetuses of Diabetic and Non-Diabetic Mothers Using Tissue Doppler Imaging

Maryam Moradian 1 , Avisa Tabib 2 , Ahmad Ghasempour 1 , * , Nasrin Alaee 1 and Zahra Akbarzadeh 1
Authors Information
1 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran
2 Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran
Article information
  • Research in Cardiovascular Medicine: November 2016, 5 (4); e31864
  • Published Online: January 20, 2016
  • Article Type: Research Article
  • Received: July 27, 2015
  • Revised: October 17, 2015
  • Accepted: October 27, 2015
  • DOI: 10.5812/cardiovascmed.31864

To Cite: Moradian M, Tabib A, Ghasempour A, Alaee N, Akbarzadeh Z. et al. Comparing Ventricular Function in Fetuses of Diabetic and Non-Diabetic Mothers Using Tissue Doppler Imaging, Res Cardiovasc Med. 2016 ;5(4):e31864. doi: 10.5812/cardiovascmed.31864.

Copyright: Copyright © 2016, Research in Cardiovascular Medicine. .
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Hornberger LK. Maternal diabetes and the fetal heart. Heart. 2006; 92(8): 1019-21[DOI][PubMed]
  • 2. Greco P, Vimercati A, Scioscia M, Rossi AC, Giorgino F, Selvaggi L. Timing of fetal growth acceleration in women with insulin-dependent diabetes. Fetal Diagn Ther. 2003; 18(6): 437-41[PubMed]
  • 3. Ferrara A. Increasing prevalence of gestational diabetes mellitus: a public health perspective. Diabetes Care. 2007; 30 Suppl 2-6[DOI][PubMed]
  • 4. Tabib A, Shirzad N, Sheikhbahaei S, Mohammadi S, Qorbani M, Haghpanah V, et al. Cardiac malformations in fetuses of gestational and pre gestational diabetic mothers. Iran J Pediatr. 2013; 23(6): 664-8[PubMed]
  • 5. Pedra SR, Smallhorn JF, Ryan G, Chitayat D, Taylor GP, Khan R, et al. Fetal cardiomyopathies: pathogenic mechanisms, hemodynamic findings, and clinical outcome. Circulation. 2002; 106(5): 585-91[PubMed]
  • 6. Lisowski LA, Verheijen PM, De Smedt MM, Visser GH, Meijboom EJ. Altered fetal circulation in type-1 diabetic pregnancies. Ultrasound Obstet Gynecol. 2003; 21(4): 365-9[DOI][PubMed]
  • 7. Wong SF, Chan FY, Cincotta RB, McIntyre HD, Oats JJ. Cardiac function in fetuses of poorly-controlled pre-gestational diabetic pregnancies--a pilot study. Gynecol Obstet Invest. 2003; 56(2): 113-6[PubMed]
  • 8. Classification and Diagnosis of Diabetes. 2015;
  • 9. Radder JK, van Roosmalen J. HbA1c in healthy, pregnant women. Neth J Med. 2005; 63(7): 256-9[PubMed]
  • 10. Nashaat EH, Mansour GM. Uncontrolled diabetes mellitus and fetal heart. Researcher. 2010; 2(5): 45-55
  • 11. Liu F, Liu S, Ma Z, Zhan X, Tao G, Cheng L, et al. Assessment of left ventricular systolic function in fetuses without myocardial hypertrophy of gestational diabetes mellitus mothers using velocity vector imaging. J Obstet Gynaecol. 2012; 32(3): 252-6[DOI][PubMed]
  • 12. Simpson J. Speckle tracking for the assessment of fetal cardiac function. Ultrasound Obstet Gynecol. 2011; 37(2): 133-4[DOI][PubMed]
  • 13. Zielinsky P, Nicoloso LH, Firpo C, Marcantonio S, Scheid M, Gus EI, et al. Alternative parameters for echocardiographic assessment of fetal diastolic function. Braz J Med Biol Res. 2004; 37(1): 31-6[PubMed]
  • 14. Hatem MA, Zielinsky P, Hatem DM, Nicoloso LH, Manica JL, Piccoli AL, et al. Assessment of diastolic ventricular function in fetuses of diabetic mothers using tissue Doppler. Cardiol Young. 2008; 18(3): 297-302[DOI][PubMed]
  • 15. Narchi H, Kulaylat N. Heart disease in infants of diabetic mothers. Images Paediatr Cardiol. 2000; 2(2): 17-23[PubMed]
  • 16. Corrigan N, Brazil DP, McAuliffe F. Fetal cardiac effects of maternal hyperglycemia during pregnancy. Birth Defects Res A Clin Mol Teratol. 2009; 85(6): 523-30[DOI][PubMed]
  • 17. Allen HD, Driscoll RE, Shaddy RE, Feltes TF. Moss & Adams' Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adult . 2013;
  • 18. Gardiner HM, Pasquini L, Wolfenden J, Kulinskaya E, Li W, Henein M. Increased periconceptual maternal glycated haemoglobin in diabetic mothers reduces fetal long axis cardiac function. Heart. 2006; 92(8): 1125-30[DOI][PubMed]
  • 19. Vogel M, Cheung MM, Li J, Kristiansen SB, Schmidt MR, White PA, et al. Noninvasive assessment of left ventricular force-frequency relationships using tissue Doppler-derived isovolumic acceleration: validation in an animal model. Circulation. 2003; 107(12): 1647-52[DOI][PubMed]
  • 20. Walther FJ, Siassi B, King J, Wu PY. Cardiac output in infants of insulin-dependent diabetic mothers. J Pediatr. 1985; 107(1): 109-14[PubMed]
  • 21. Tincello D, White S, Walkinshaw S. Computerised analysis of fetal heart rate recordings in maternal type I diabetes mellitus. BJOG. 2001; 108(8): 853-7[PubMed]
  • 22. Bolognesi M. Overdiagnosis of Gestational Diabetes Mellitus in Pregnant Woman: A Case Report. J Women’s Health Care. 2015; 4(234): 2167
  • 23. Moses RG. New consensus criteria for GDM: problem solved or a pandora's box? Diabetes Care. 2010; 33(3): 690-1[DOI][PubMed]
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